Showing posts with label Genetic. Show all posts
Showing posts with label Genetic. Show all posts

Wednesday, September 10, 2008

What is a Clubfoot or Feet?

A clubfoot, or talipes equinovarus (TEV), is a birth defect. The foot is twisted in (inverted) and down. Without treatment , persons afflicted often appear to walk on their ankles, or on the sides of their feet. It is a common birth defect, occurring in about 1 in every 1,000 live births.

Approximately 50% of cases of clubfoot are bilateral. In most cases it is an isolated dysmelia. Incidence in males is higher than in females.

There are different causes for clubfoot: Mainly caused by Edwards' syndrome, a genetic defect with 3 copies of chromosome 18 genetic causes with incidence rates increasing significantly when multiple direct family members have the condition external influences such as intrauterine compression from oligohydramnios or from amniotic band syndrome.

Clubfoot is treated with manipulation largely by a podiatrist, sometimes an orthopedic surgeons, specialist nurses, or orthotists, will treat the condition by providing FAB braces to hold the feet in orthodox positions, serial casting, or small splints called knee ankle foot orthoses(KAFO).

After correction has been achieved, maintenance of correction may require the full-time (23 hours per day) use of a splint—also known as a foot abduction brace (FAB)—on both feet, regardless or whether the TEV is on one side or both, for several weeks after treatment. Part-time use of a brace (generally at night, usually 12 hours per day) is frequently prescribed for up to 4 years.

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Sunday, July 6, 2008

What is Obsessive Compulsive Disorder?

Obsessive Compulsive Disorder (OCD) is a psychiatric disorder, specifically, an anxiety disorder. OCD is manifested in a variety of forms, but is most commonly characterized by a subject's obsessive drive to perform a particular task or set of tasks, compulsions commonly termed rituals.

The phrase "obsessive-compulsive" has worked its way into the wider English lexicon, and is often used in an offhand manner to describe someone who is meticulous or absorbed in a cause.

People who suffer from the separate and unrelated condition obsessive compulsive personality disorder are not aware of anything abnormal with them; they will readily explain why their actions are rational, and it is usually impossible to convince them otherwise.

Although obsessive-compulsive disorder commonly occurs in many patients with Gilles de la Tourette's syndrome, little is known about the obsessions and compulsions of Tourette's syndrome and whether they differ from those seen in pure obsessive-compulsive disorder.

It is for this reason there is some overlap between this category and our Famous People with Tourettes Syndrome list.

The tic disorder Tourette's Syndrome (T S) and Obsessive-Compulsive Disorder (OCD) are genetic and/or autoimmune neurological syndromes1,2,3 which are comorbid (In medicine, comorbidity describes the effect of all other diseases an individual patient might have other than the primary disease of interest) in 40-75% of patients initially diagnosed with either disorder, with comorbidity (In medicine, comorbidity describes the effect of all other diseases an individual patient might have other than the primary disease of interest) likeliest to occur in their childhood-onset forms.

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Saturday, June 7, 2008

What is Tourettes Syndrome?

Tourette syndrome (also called Tourette's syndrome, Tourette's disorder, Gilles de la Tourette syndrome, GTS or, more commonly, simply Tourette's or TS) is an inherited neurological disorder with onset in childhood, characterized by the presence of multiple physical (motor) tics and at least one vocal (phonic) tic; these tics characteristically wax and wane.

The exact cause of Tourette's is unknown, but it is well established that both genetic and environmental factors are involved. Genetic studies have shown that the overwhelming majority of cases of Tourette's are inherited, although the exact mode of inheritance is not yet known, and no gene has been identified.

Tourette's was once considered a rare and bizarre syndrome, most often associated with the exclamation of obscene words or socially inappropriate and derogatory remarks (coprolalia). However, this symptom is present in only a small minority of people with Tourette's.
A person with Tourette's has about a 50% chance of passing the gene(s) to one of his or her children.

We, www.lifechums.com/ are now going to provide a wealth of information of Famous People to send out a positive message to all Disabled People.

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