Charles V of Spain was born on 24 February 1500 and died on 21 September 1558. Charles was ruler of the Holy Roman Empire from 1519 until his abdication in 1556 and also ruler of the Spanish realms from 1516 until 1556.Charles V suffered from epilepsy and from an enlarged lower jaw. He struggled to chew his food properly and consequently experienced bad indigestion for much of his life. Charles also suffered from joint pain, presumed to be gout, according to his 16th century doctors. In his retirement, he was carried around the monastery of St. Yuste in a sedan chair. He was greatly interested in clocks, instructing his servants to take them apart and reassemble them in his presence.
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